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Vaccine Weekly

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Flu Vaccines



Research from Groningen University yields new findings on flu vaccines



December 17th, 2008

According to recent research from Netherlands, "In the case of an influenza pandemic, the current global influenza vaccine production capacity will be unable to meet the demand for billions of vaccine doses. The ongoing threat of an H5N1 pandemic therefore urges the development of highly immunogenic, dose-sparing vaccine formulations."

"In unprimed individuals, inactivated whole virus (WIV) vaccines are more immunogenic and induce protective antibody responses at a lower antigen dose than other formulations like split virus (SV) or subunit (SU) vaccines. The reason for this discrepancy in immunogenicity is a long-standing enigma. Here, we show that stimulation of...


Source: Vaccine Weekly (2008-12-17)

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