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Vaccine Weekly

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Fusion Proteins



New fusion proteins research from D. Liu and colleagues discussed



December 17th, 2008

"The gene fragment coding for Arbor Acres (AA) chicken C3d gene (chC3d) was cloned and expressed as a component of fusion proteins for its potential use as a vaccine for chickens and for in vitro experiments. This fragment of complement protein C3 (C3d) has been shown to strengthen B-cell responses when complexed with antigen," investigators in Shandong, People's Republic of China report.

"Three potential vaccine constructs were engineered to contain two, four, and six copies of chC3d-P29 coding gene, which was linked to the F gene of Newcastle disease virus (NDV), an economically important pathogen of chicken that is classified as a class A contagious disease of...


Source: Vaccine Weekly (2008-12-17)

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