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DNA Vaccines
SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial
December 24th, 2008
Vical Incorporated (NASDAQ:VICL) announced that results from a Phase I clinical trial of a DNA vaccine for severe acute respiratory syndrome (SARS), conducted by the National Institutes of Health (NIH) and published in the November 25 issue of Vaccine(1), demonstrated that the vaccine was well-tolerated, and induced neutralizing antibody responses in 80% of the vaccinees and T-cell immune responses in all vaccinees. The Phase I trial was initiated with unprecedented speed, within 19 months of the publication of the SARS coronavirus genetic sequence from which the vaccine was derived, and was the first SARS vaccine human clinical trial conducted in the United States. The...
Source: Vaccine Weekly (2008-12-24)
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