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Vaccine Weekly

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Immunization



Research from University of Texas provides new data on immunization



December 24th, 2008

"Rift Valley fever virus (RVFV) is a member of the Bunyaviridae virus family ( genus Phlebovirus) and is considered to be one of the most important pathogens in Africa, causing viral zoonoses in livestock and humans. Here, we report the characterization of the three-dimensional structural organization of RVFV vaccine strain MP-12 by cryoelectron tomography," scientists in the United States report.

"Vitrified-hydrated virions were found to be spherical, with an average diameter of 100 nm. The virus glycoproteins formed cylindrical hollow spikes that clustered into distinct capsomeres. In contrast to previous assertions that RVFV is pleomorphic, the structure of RVFV...


Source: Vaccine Weekly (2008-12-24)

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