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Hepatitis A Virus



Scientists at University Hospital report research in hepatitis A virus



December 24th, 2008

"Over the last few decades, different types of inactivated hepatitis A virus (HAV) vaccines have been developed: several aluminum-adjuvanted vaccines and an aluminum-free, virosome-formulated vaccine. Both types of vaccines are whole-virus preparations that are produced by growth of HAV strains in human diploid cell cultures and are subsequently inactivated with formaldehyde," investigators in Geneva, Switzerland report.

"This review summarizes all published papers on a virosome-formulated vaccine, Epaxal(R), based on formalin inactivated HAV (strain RG-SB) adsorbed to the surface of special liposomes (virosomes), that replace aluminum hydroxide as the adjuvant...


Source: Vaccine Weekly (2008-12-24)

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