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Vaccine Weekly

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Influenza



Data on influenza detailed by D.M.A. Gendoo and co-authors



December 24th, 2008

"Variations in the influenza Hemagglutinin protein contributes to antigenic drift resulting in decreased efficiency of seasonal influenza vaccines and escape from host immune response. We performed an in silico study to determine characteristics of novel variable and conserved motifs in the Hemagglutinin protein from previously reported H3N2 strains isolated from Hong Kong from 1968-1999 to predict viral motifs involved in significant biological functions," scientists in Cairo, Egypt report.

"14 MEME blocks were generated and comparative analysis of the MEME blocks identified blocks 1, 2, 3 and 7 to correlate with several biological functions. Analysis of the different...


Source: Vaccine Weekly (2008-12-24)

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