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Vaccine Weekly

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Influenza



Researchers from University of Tokyo discuss findings in influenza



December 24th, 2008

"H5N1 influenza A viruses are exacting a growing human toll, with more than 240 fatal cases to date. In the event of an influenza pandemic caused by these viruses, embryonated chicken eggs, which are the approved substrate for human inactivated-vaccine production, will likely be in short supply because chickens will be killed by these viruses or culled to limit the worldwide spread of the infection," investigators in Tokyo, Japan report.

"The Madin-Darby canine kidney (MDCK) cell line is a promising alternative candidate substrate because it supports efficient growth of influenza viruses compared to other cell lines. Here, we addressed the molecular determinants for...


Source: Vaccine Weekly (2008-12-24)

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