Salmonellosis Vaccines
Study results from University of Pecs broaden understanding of salmonellosis vaccines
Published in Vaccine Weekly, December 24th, 2008
Scientists discuss in "Gently rough"the vaccine potential of a Salmonella enterica regulatory lipopolysaccharide mutant' new findings in salmonellosis. According to a study from Pecs, Hungary, "An alternative to multivalent vaccines could be to construct strains capable of conferring broad protection through shared antigens. Down-regulation of immunodominant major antigens has been proposed to enhance the immunogenicity of conserved antigens."
"The protection provided by an aroA as well as structural and regulatory lipopolysaccharide (LPS) mutants of Salmonella enterica serovar Typhimurium against homologous and heterologous challenges was assessed in the murine model...
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Source: Vaccine Weekly (2008-12-24)
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