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Immunization
New immunization study findings have been reported by scientists at University Hospital
December 31st, 2008
Current study results from the report, 'Comparison of the immunomodulatory effects of L. donovani and L. major excreted-secreted antigens, particulate and soluble extracts and viable parasites on human dendritic cells,' have been published. According to recent research from Rennes, France, "In an experimental model of human monocyte-derived dendritic cells (DCs), the immunophenotype of mature DCs infected with Leishmania donovani and Leishmania major showed a weak decrease in the cell surface expression of CD40, CD86, HLA-DR and DC-SIGN compared with uninfected control DCs." "This immunomodulatory effect was more pronounced after stimulation with...
Source: Vaccine Weekly (2008-12-31)
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