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Vaccine Weekly

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Malaria Vaccines



Research conducted at University of Edinburgh has provided new information about malaria vaccines



December 31st, 2008

Data detailed in 'Mixed allele malaria vaccines: host protection and within-host selection' have been presented. According to recent research published in the journal Vaccine, "Malaria parasites are frequently polymorphic at the antigenic targets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses. Conventional wisdom is therefore that vaccines directed against a single variant could select for non-target variants, rendering the vaccine useless."

"Many people have argued that a solution is to develop vaccines containing the products of more than one variant of the target. However, we are unaware of any...


Source: Vaccine Weekly (2008-12-31)

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