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Salmonellosis Vaccines
Research from University of Melbourne broadens understanding of salmonellosis vaccines
December 31st, 2008
Scientists discuss in 'Impact of prior immunological exposure on vaccine delivery by Salmonella enterica serovar Typhimurium' new findings in salmonellosis. "Recombinant Salmonella have been employed as vaccine vectors to deliver DNA and protein vaccines of viral, bacterial and parasitic origin. However, the effectiveness of Salmonella delivery may be hampered by prior immunological exposure to Salmonella," scientists writing in the journal Vaccine report. "We investigated the effects of prior exposure to the Salmonella typhimurium aroAD strain BRD509 on its ability to deliver the non-toxic C fragment of tetanus toxin (TT). BALB/c mice were orally...
Source: Vaccine Weekly (2008-12-31)
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