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Vaccine Weekly

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Vaccines



Research from Biological Mimetics, Inc. has provided new data on vaccines



December 31st, 2008

A report, 'Deceptive imprinting and immune refocusing in vaccine design,' is newly published data in Vaccine. According to a study from the United States, "A large number of the world's most widespread and problematic pathogens evade host immune responses by inducing strain-specific immunity to immunodominant epitopes with high mutation rates capable of altering antigenic profiles. The immune system appears to be decoyed into reacting to these immunodominant epitopes that offer little cross protection between serotypes or subtypes."

"For example, during HIV-1 infection, the immune system reacts strongly to the V1, V2, and/or V3 loops of the surface envelope...


Source: Vaccine Weekly (2008-12-31)

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