Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Life Sciences
Research on life sciences detailed by scientists at National Institutes of Health
January 7th, 2009
"Systemic immunization of macaques with a combination of DNA-poxvirus-based vaccines confers protection from high level of both systemic and mucosal viral replication following rectal exposure to the pathogenic SIVmac251. Here we investigated early post-infection events in rectal and vaginal tissues, and found that the loss of CCR5(+) CD4(+) T cells was equivalent in vaccinated and control macaques, despite a three logs reduction at mucosal sites of simian immunodeficiency virus (SIV) RNA in the vaccinated group," scientists in the United States report. "Even though a normal CD4(+) T cell number is not reconstituted at mucosal sites in either group, vaccination appeared...
Source: Vaccine Weekly (2009-01-07)
|
