Vaccines

Research from Hacettepe University in vaccines provides new insights

Published in Vaccine Weekly, January 7th, 2009

According to recent research from Ankara, Turkey, "Mucosal application of a vaccine can effectively induce both systemic and mucosal immune responses. In general, mucosal applications of antigens result in poor immune responses."

"Therefore, adjuvant/delivery systems are required to enhance the immune response. Chitosan is a cationic biopolymer which exerts advantages as a vaccine carrier due to its immune stimulating activity and bioadhesive properties that enhance cellular uptake and permeation as well as antigen protection. Similar effects are also shown by chitosan derivatives. In this study, the nanoparticulate systems were prepared by using differently charged...

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Source: Vaccine Weekly (2009-01-07)

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