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Cancer Vaccines
Research from Shanghai Jiao Tong University in the area of cancer vaccines published
January 7th, 2009
Researchers in Shanghai, People's Republic of China conducted a study "To investigate the antitumor immunity by a dendritic cell (DC) vaccine encoding secondary lymphoid chemokine gene and tumor lysate on murine prostate cancer. DC from bone marrow of C57BL/6 were transfected with a plasmid vector expressing secondary lymphoid chemokine (SLC) cDNA by Lipofectamine2000 liposome and tumor lysate." "Total RNA extracted from SLC+lysate-DC was used to verify the expression of SLC by reverse transcriptase-polymerase chain reaction (RT-PCR). The immunotherapeutic effect of DC vaccine on murine prostate cancer was assessed. We found that in the prostate tumor model of C57BL/6...
Source: Vaccine Weekly (2009-01-07)
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