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Vaccine Weekly

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Apoptosis



Research from L. Bertaux and colleagues has provided new data on apoptosis



January 7th, 2009

According to recent research from Tours, France, "Infection with the intracellular protozoan parasite Toxoplasma gondii may cause severe sequelae in foetuses and life-threatening neuropathy in immunocompromised patients. We recently reported that vaccination with T. gondii-pulsed dendritic cells induces protective humoral and cellular immune responses against this intracellular pathogen in CBA/J mice."

"We assessed the feasibility of using a nonlive vaccine, by inducing the apoptosis of T. gondii-pulsed dendritic cells before injecting them into mice. Apoptosis was induced by culturing cells to confluence. We investigated whether these apoptotic T. gondii-pulsed...


Source: Vaccine Weekly (2009-01-07)

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