Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Flu Vaccines
Investigators at University of Melbourne target flu vaccines
January 7th, 2009
According to a study from Melbourne, Australia, "Using a large animal model, we evaluated whether delivery of influenza vaccine via its mucosal site of infection could improve vaccine effectiveness. Unexpectedly, pulmonary immunization with extremely low antigen doses (0.04 mu g influenza) induced serum antibody levels equivalent to those resulting from a current human vaccine equivalent (15 mu g unadjuvanted influenza, subcutaneously) and vastly superior lung mucosal antibodies." "Induction of this potent response following lung vaccination was dependent on addition of ISCOMATRIX adjuvant and deep lung delivery. Functional antibody activity, marked by hemagglutination...
Source: Vaccine Weekly (2009-01-07)
|
