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Herpesvirus
New herpesvirus data have been reported by researchers at University of California
January 14th, 2009
According to recent research published in the Journal of Virology, "The identification of ''asymptomatic'' (i.e., protective) epitopes recognized by T cells from herpes simplex virus (HSV)-seropositive healthy individuals is a prerequisite for an effective vaccine. Using the PepScan epitope mapping strategy, a library of 179 potential peptide epitopes (15-mers overlapping by 10 amino acids) was identified from HSV type 1 (HSV-1) glycoprotein B (gB), an antigen that induces protective immunity in both animal models and humans." "Eighteen groups (G1 to G18) of 10 adjacent peptides each were first screened for T-cell antigenicity in 38 HSV-1-seropositive but...
Source: Vaccine Weekly (2009-01-14)
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