Leprosy

New leprosy findings from M.S. Duthie and co-authors described

Published in Vaccine Weekly, January 14th, 2009

According to recent research from the United States, "The identification of human T-cell antigens of Mycobacterium leprae could improve treatment and help to disrupt the transmission of leprosy by directing diagnosis and vaccine programs. This study screened a panel of M. leprae recombinant proteins for T-cell recall responses, measured by gamma interferon (IFN-gamma) production, among leprosy patients."

"After initial studies using peripheral blood mononuclear cells from leprosy patients, we transitioned our studies to simple whole-blood assays (WBA), which are more applicable in field or clinical settings. T-cell responses generated in WBA using blood from individuals...

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Source: Vaccine Weekly (2009-01-14)

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