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Cell Therapy
Studies from Yonsei University, Cell Therapy Center in the area of cell therapy published
January 14th, 2009
"Despite the increasing use of dendritic cell (DC) vaccination in clinical trials, optimal conditions for the generation of functionally mature DCs remain to be established. The current standard DC maturation protocol for clinical trials has been used as an inflammatory cytokine cocktail [tumour necrosis factor (TNF)-alpha, interleukin (IL)-1 beta, IL-6 and prostaglandin E-2], but this cocktail induced insufficient maturation of DCs derived from elutriated monocytes when cultured in X-VIVO 15," scientists in Seoul, South Korea report. "The aim of this study was to define effective combinations of stimulators for generating functionally mature DCs from elutriated...
Source: Vaccine Weekly (2009-01-14)
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