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Vaccine Weekly

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Nipah Virus



New nipah virus research from University of Oxford outlined



January 14th, 2009

"Two members of the paramyxovirus family, Nipah virus (NiV) and Hendra virus (HeV), are recent additions to a growing number of agents of emergent diseases which use bats as a natural host. Identification of ephrin-B2 and ephrin-B3 as cellular receptors for these viruses has enabled the development of immunotherapeutic reagents which prevent virus attachment and subsequent fusion," scientists in Oxford, the United Kingdom report.

"Here we present the structural analysis of the protein and carbohydrate components of the unbound viral attachment glycoprotein of NiV glycoprotein (NiV-G) at a 2.2-angstrom resolution. Comparison with its ephrin-B2-bound form reveals that...


Source: Vaccine Weekly (2009-01-14)

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