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Immunization
Research results from University of Bristol update knowledge of immunization
January 14th, 2009
A new study, 'Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases,' is now available. According to recent research from Bristol, the United Kingdom, "Choline-binding protein A (CbpA) and pneumolysin (Ply) can induce the expression and release of chemokines by human cells, which might modulate specific immune responses. In dendritic cells (DCs), such effects could be important for the size and character of the immunity induced if administered as vaccines." "We studied the induction of CCL and CXCL...
Source: Vaccine Weekly (2009-01-14)
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