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Vaccine Weekly

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Hepatitis B Virus



Reports outline hepatitis B virus research from J.M. Pascasio and colleagues



January 14th, 2009

According to recent research from Seville, Spain, "We conducted a retrospective study to evaluate the response to recombinant hepatitis B vaccine after 4 intramuscular doses (40 jig) administered at 0, 1, 2, and 6 months in 157 cirrhotic patients who were liver transplant candidates. Seventeen nonresponders were revaccinated with the same schedule."

"We studied the association between the following variables and the vaccine response: age, gender, etiology of cirrhosis, diabetes, severity of liver disease (Child-Pugh class and Model for End-Stage Liver Disease [MELD] score), and the number of administered doses. The response rates were: 1 dose, 40% (2/5); 2 doses, 0%...


Source: Vaccine Weekly (2009-01-14)

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