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Hepatitis C Virus
Reports outline hepatitis C virus study results from D. Yerly et al
January 14th, 2009
"Hepatitis C virus (HCV) vaccine efficacy may crucially depend on immunogen length and coverage of viral sequence diversity. However, covering a considerable proportion of the circulating viral sequence variants would likely require long immunogens, which for the conserved portions of the viral genome, would contain unnecessarily redundant sequence information," scientists in Barcelona, Spain report. "In this study, we present the design and in vitro performance analysis of a novel ''epitome'' approach that compresses frequent immune targets of the cellular immune response against HCV into a shorter immunogen sequence. Compression of immunological information is...
Source: Vaccine Weekly (2009-01-14)
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