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Vaccines
Studies from University of Alabama provide new data on vaccines
January 21st, 2009
According to recent research published in the Journal of Leukocyte Biology, "Francisella tularensis is the causative agent of tularemia, a severe, debilitating disease of humans and other mammals. As this microorganism is also classified as a ''category-A pathogen'' and a potential biowarfare agent, there is a need for an effective vaccine." "Several antigens of F. tularensis, including the heat shock protein DnaK, have been proposed for use in a potential subunit vaccine. In this study, we characterized the innate immune response of murine bone marrow-derived dendritic cells ( DC) to F. tularensis DnaK. Recombinant DnaK was produced using a bacterial expression...
Source: Vaccine Weekly (2009-01-21)
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