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Vaccine Weekly

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Cancer Vaccines



Studies from Drexel University, Medical Department yield new data on cancer vaccines



January 21st, 2009

According to a study from the United States, "Despite cervical cancer being considered a preventable disease, it still remains the second most common malignancy in women worldwide, with a higher incidence in underdeveloped countries. Human papillomavirus (HPV) is considered the causative agent of cervical cancer."

"The major mechanisms through which HPV contributes to neoplastic initiation and progression include the activity of 2 viral oncoproteins, E6 and E7, which interfere with critical cell cycle tumor suppressive proteins, p53 and retinoblastoma (Rb) protein. However, HPV infection alone is not sufficient to induce malignant transformation, and other significant...


Source: Vaccine Weekly (2009-01-21)

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