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Gene Therapy
Findings from University of California, California National Primate Research Center in gene therapy reported
January 21st, 2009
Researchers detail in 'A heterologous DNA prime/protein boost immunization strategy for rhesus cytomegalovirus,' new data in gene therapy. According to recent research published in the journal Vaccine, "A previous study in nonhuman primates demonstrated that genetic immunization against the rhesus cytomegalovirus phosphoprotein 65-2 (pp65-2) and glycoprotein B (gB) antigens both stimulated antigen-specific antibodies and CD8 T cell responses, and significantly reduced plasma viral loads following intravenous challenge with RhCMV. It was also noted in this study that weak CD4 T cell and neutralizing antibody responses were generated by DNA alone." "To broaden the...
Source: Vaccine Weekly (2009-01-21)
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