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DNA Vaccines
Reports from E.J. Emmenegger and colleagues advance knowledge in DNA vaccines
January 28th, 2009
"The emergence of spring viremia of carp virus (SVCV) in the United States constitutes a potentially serious alien pathogen threat to susceptible fish stocks in North America. A DNA vaccine with an SVCV glycoprotein (G)gene from a North American isolate was constructed," scientists in the United States report. "In order to test the vaccine a challenge model utilizing a specific pathogen-free domestic koi stock and a cold water stress treatment was also developed. We have conducted four trial studies demonstrating that the pSGnc DNA vaccine provided protection in vaccinated fish against challenge at low, moderate, and high virus doses of the homologous virus. The...
Source: Vaccine Weekly (2009-01-28)
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