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Vaccine Weekly

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Autoimmune Disease Vaccines



Researchers from University of Bristol describe findings in autoimmune disease vaccines



January 28th, 2009

Current study results from the report, 'Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations,' have been published. "Experimental autoimmune uveoretinitis (EAU) is an animal model for human intraocular inflammatory disease. EAU is induced in B10.RIII mice by immunization with RBP-3 161-180 peptide and intraperitoneal pertussis toxin and is mediated by CD4(+) T cells that generate a clinically monophasic disease peaking approximately 2 weeks post-immunization," scientists writing in the Journal of Autoimmunity report.

"Collagenase digestion of retinal tissue allowed the quantification and...


Source: Vaccine Weekly (2009-01-28)

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