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Vaccine Weekly

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Immunization



Research from Dartmouth University yields new findings on immunization



January 28th, 2009

Research findings, 'Variable gene family usage of protective and non-protective anti-Vibrio cholerae O1 LPS antibody heavy chains,' are discussed in a new report. "Vibrio cholerae causes cholera, an enteric disease of humans that is a worldwide problem. The O1 serogroup of Vibrio cholerae contains two predominant serotypes (Inaba and Ogawa) of LPS, a proven protective antigen for humans and experimental animals," researchers in Lebanon report.

"We generated B-cell hybridomas from mice immunized with either: (i) two doses of purified Inaba LPS; (ii) two doses of an Inaba hexasaccharide conjugate (terminal six perosamine bound to a protein carrier), (iii)...


Source: Vaccine Weekly (2009-01-28)

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