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Life Sciences



New life sciences research has been reported by C. Manzano et al



January 28th, 2009

A report, 'Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae,' is newly published data in Structure. According to recent research from Grenoble, France, "Streptococcus pneumoniae is a piliated pathogen whose ability to circumvent vaccination and antibiotic treatment strategies is a cause of mortality worldwide. Pili play important roles in pneumococcal infection, but little is known about their biogenesis mechanism or the relationship between components of the pilus-forming machinery, which includes the fiber pilin (RrgB), two minor pilins (RrgA, RrgC), and three sortases (SrtC-1, SrtC-2, SrtC-3)."

"Here we show that SrtC-1 is the main...


Source: Vaccine Weekly (2009-01-28)

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