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Vaccine Weekly

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Lyme Disease



Study data from T.B. Ledue et al provide new insights into lyme disease



February 4th, 2009

"Recent efforts to improve the serologic diagnosis of Lyme disease have included the use of a synthetic peptide (C6) that reproduces the sequence of invariable region 6 of VlsE, the variable surface antigen of Borrelia burgdorferi. In the present study, the diagnostic performance of DiaSorin's recombinant VlsE-based chemiluminescence immunoassay in 1,947 human serum samples was evaluated," scientists writing in the journal Clinical and Vaccine Immunology report.

"Sensitivity was determined using two serum panels from the CDC. For panel I, we observed sensitivities of 68.4% and 75.6% for subjects with early, localized (n = 19) or disseminated (n = 41) disease,...


Source: Vaccine Weekly (2009-02-04)

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