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Vaccine Weekly

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Tetanus



Research conducted at K.H. Vanhoeven and co-researchers has updated our knowledge about tetanus



February 4th, 2009

"Accurate determination of the concentrations of immunoglobulin G (IgG) antibody to tetanus toxoid is important in order to evaluate the immunogenicity of tetanus toxoid vaccines, determine immune competence in individual patients, and measure the prevalence of immunity in populations. The performance of three commercially available enzyme-linked immunosorbent assays (ELISAs) for IgG antibodies to tetanus toxoid were evaluated," scientists writing in the journal Clinical and Vaccine Immunology report.

"Serially diluted NIBSC 76/589 and TE-3 human tetanus IgG immunoglobulin international reference standards were analyzed in quadruplicate using ELISAs manufactured...


Source: Vaccine Weekly (2009-02-04)

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