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Vaccine Weekly

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Vaccine Efficacy



Reports from N.E. Basta and colleagues advance knowledge in vaccine efficacy



February 4th, 2009

"In this paper, the authors provide estimates of 4 measures of vaccine efficacy for live, attenuated and inactivated influenza vaccine based on secondary analysis of 5 experimental influenza challenge studies in seronegative adults and community-based vaccine trials. The 4 vaccine efficacy measures are for susceptibility (VES), symptomatic illness given infection (VEP), infection and illness (VESP), and infectiousness (VEI)," scientists in the United States report.

"The authors also propose a combined (VEC) measure of the reduction in transmission in the entire population based on all of the above efficacy measures. Live influenza vaccine and inactivated vaccine...


Source: Vaccine Weekly (2009-02-04)

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