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Vaccine Weekly

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Vaccines



Research conducted at Jawaharlal Nehru University has updated our knowledge about vaccines



February 4th, 2009

Current study results from the report, 'A very large C-loop in EGF domain IV is characteristic of the P28 family of ookinete surface proteins,' have been published. "The P28 family of proteins are 28 kDa proteins expressed on the surface of sexual stages--zygote, ookinete and young oocyst stages--of Plasmodium species when the parasite resides inside the mosquito midgut. Together with P25 proteins, P28 proteins protect the parasite from the harsh proteolytic environment prevailing inside the mosquito midgut," scientists writing in the Journal of Molecular Modeling report.

"Vaccines against these proteins induce antibodies in vertebrate hosts that are capable of...


Source: Vaccine Weekly (2009-02-04)

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