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Enzyme Research
Data on enzyme research published by researchers at University of Milan
February 4th, 2009
"Skin immunosenescence accounts for increased susceptibility in the elderly to cutaneous infections and malignancies, and decreased contact hypersensitivity and response to vaccination. We have recently shown in immune cells that decreased expression of the receptor for activated C kinase (RACK)-1 underlies defective protein kinase C (PKC) activation and functional immune impairment with aging," scientists in Milan, Italy report. "This study was designed to determine if an age-related decline in skin RACK-1 expression was present and whether it correlated with defective tumour necrosis factor (TNF)-alpha production. PKC isoforms and RACK-1 expression were evaluated by...
Source: Vaccine Weekly (2009-02-04)
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