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Vaccines
Reports outline vaccines research from University of Colorado
February 4th, 2009
According to a study from the United States, "The purpose of this study was to evaluate the importance of prelyophilization solution pH on the stability of botulinum neurotoxin, serotype A (rBoNTA(H-c)). This understanding is of significant importance for proteins such as rBoNTA(H-c), a potential constituent of a multivalent vaccine product." "For multivalent vaccines it may be difficult to identify a liquid formulation satisfying the stability requirements for all constituent protein antigens. Consequently, a lyophilized multivalent vaccine formulation may be a more viable alternative. Therefore evaluating the effect of prelyophilization pH (may be suboptimal) on the...
Source: Vaccine Weekly (2009-02-04)
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