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Vaccine Weekly

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Falciparum Malaria



Research findings from University of California update understanding of falciparum malaria



February 4th, 2009

"A complete description of the serological. response following exposure of humans to complex pathogens is lacking and approaches suitable for accomplishing this are limited. Here we report, using malaria as a model, a method which elucidates the profile of antibodies that develop after natural or experimental infection or after vaccination with attenuated organisms, and which identifies immunoreactive antigens of interest for vaccine development or other applications," researchers in the United States report.

"Expression vectors encoding 250 Plasmodium falciparum (Pf) proteins were generated by PCR/recombination cloning; the proteins were individually expressed with...


Source: Vaccine Weekly (2009-02-04)

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