Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Foot and Mouth Disease
Study results from Z.J. Lu and colleagues update understanding of foot and mouth disease
February 11th, 2009
"Two recombinant adenoviruses were constructed expressing foot-and-mouth disease virus (FMDV) capsid and 3C/3CD proteins in replicative deficient human adenovirus type 5 vector. Guinea pigs vaccinated with 1-3 x 10(8) TCID50 Ad-P12 x 3C recombinant adenovirus were completely protected against 10,000 GID(50) homologous virulent FMDV challenge 25 days post vaccination (dpv)," researchers in Lanzhou, People's Republic of China report. "Ad-P12 x 3CD vaccinated guinea pigs were only partially protected. Swine were vaccinated once with 1 x 10(9) TCID50 Ad-P12 x 3C hybrid virus and challenged 28 days later. Three of four vaccinated swine were completely protected against 200...
Source: Vaccine Weekly (2009-02-11)
|
