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Immunization
Studies conducted at M. Cruciani et al on immunization recently published
February 11th, 2009
"Sixty-five HIV-infected patients received high-dose (40 mu g). short interval HBV vaccine. In non-responders to the initial immunization, 1-3 boosters were administered," investigators in Verona, Italy report. "Rate of response was 60.0% after primary vaccination, and 89.2% after boosters. However, 12 and 24 months after the last vaccination, only 63% and 32.7% of the responders, respectively, had persistence of protective anti-HBs titers (>= 10 IU/L). The results of logistic regression show that gender. CD4 Count, and HIV vital load were significant predictors of vaccination Outcome. This Study Suggests that in HIV-infected patients with relatively high CD4 Count,...
Source: Vaccine Weekly (2009-02-11)
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