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Vaccine Weekly

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Mycobacteria



Reports outline mycobacteria study results from Cornell University, Medical Department



February 11th, 2009

"The protective efficacy of four recombinant antigens (85A, 85B, superoxide dismutase [SOD], and a fusion polypeptide [Map74F]) of Mycobacterium avium subsp. paratuberculosis (MAP) along with the adjuvant dimethydioctadecyl aninionium bromide (DDA) was assessed in a goat challenge model. Animals were immunized with the four antigens with adjuvant DDA (Group 1, eight goat kids) or without the adjuvant (Group II, eight goat kids) or adjuvant only (Group III, nine goat kids)," scientists writing in the journal Vaccine report.

"Animals were boostered 3 weeks after the primary vaccination and challenged 3 weeks after the booster. Significant antigen-specific...


Source: Vaccine Weekly (2009-02-11)

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