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Vaccine Weekly

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Pneumococcal Disease



Researchers from University of Bern provide details of new studies and findings in the area of pneumococcal disease



February 11th, 2009

According to a study from Bern, Switzerland, "Clinical trials and meta-analyses have produced conflicting results of the efficacy of unconjugated pneumococcal polysaccharide vaccine in adults. We sought to evaluate the vaccine's efficacy on clinical outcomes as well as the methodologic quality of the trials."

"We searched several databases and all bibliographies of reviews and meta-analyses for clinical trials that compared pneumococcal polysaccharide vaccine with a control. We examined rates of pneumonia and death, taking the methodologic quality of the trials into consideration. We included 22 trials involving 101 507 participants: 11 trials reported on presumptive...


Source: Vaccine Weekly (2009-02-11)

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