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Vaccine Weekly

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Vaccines



Study findings from L. Fish et al broaden understanding of vaccines



February 11th, 2009

"Susceptible dairy cattle were immunized with attenuated, live calf-derived, in vitro-cultured or biologically cloned Babesia bovis, with non-viable exoantigens, or with recombinant rhoptry-associated protein 1 (rRAP1)," scientists in Bet Dagan, Israel report.

"Antibody response assessed by the indirect fluorescent assay (IFA) and by the growth inhibition activity in vitro showed that seroconversion correlated with neutralization activity in vitro in all immunized groups, but not with protective immunity in vivo, The protective responses elicited by immunization with completely avirulent biologically cloned live parasites, or by the exoantigens were sufficient for...


Source: Vaccine Weekly (2009-02-11)

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