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Whooping Cough
Researchers from University of Cambridge discuss findings in whooping cough
February 11th, 2009
"In a recent experiment, we found that mice previously infected with Bordetella pertussis were not protected against a later infection with Bordetella parapertussis, while primary infection with B. parapertussis conferred cross-protection. This challenges the common assumption made in most mathematical models for pathogenic strain dynamics that cross-immunity between strains is symmetric," investigators in Cambridge, the United Kingdom report. "Here we investigate the potential consequences of this pattern on the circulation of the two pathogens in human populations. To match the empirical dominance of B. pertussis, we made the additional assumption that B....
Source: Vaccine Weekly (2009-02-11)
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