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DNA Vaccines
Research in the area of DNA vaccines reported from K. Bharati and colleagues
February 11th, 2009
According to recent research from New Delhi, India, "We have previously described DNA vaccine candidates against Japanese encephalitis virus (JEV) that were immunogenic in mice, Present study was conducted to evaluate their immunogenicity in rhesus monkeys (Macuca mulatta) and compare it with the commercial mouse brain-derived, formalin-inactivated vaccine. Groups of four monkeys were immunized with either pMEa (expressing the anchored form of the envelope protein along with the pre-membrane protein of JEV) or pMEs (expressing the secretory form of the envelope protein along with pre-membrane protein of JEV) by intra-muscular (IM, using needle) or intra-dermal (ID, using gene gun)...
Source: Vaccine Weekly (2009-02-11)
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