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Falciparum Malaria
Data from H. Curtidor and colleagues advance knowledge in falciparum malaria
February 11th, 2009
"Plasmodium falciparum multi-stage proteins are involved in vital processes for parasite survival, which turns them into attractive targets for studies aimed at developing a fully effective antimalarial vaccine. MCP-1 and PfSPATR are both found in sporozoite and merozoite forms, and have been associated respectively with invasion of hepatocytes and red blood cells (RBCs)," scientists writing in the journal Biochimie report. "Binding assays with synthetic peptides derived from these two important proteins have enabled identifying those sequences binding with high specific activity (named High activity binding peptides-HABPs) to hepatoma-derived HepG2 cells and...
Source: Vaccine Weekly (2009-02-11)
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