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Vaccine Weekly

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Malnutrition



New findings from Federal University describe advances in malnutrition



February 18th, 2009

"Protein-energy malnutrition and visceral leishmaniasis are important problems of public health affecting millions of people worldwide. Vaccine efficacy depends on the ability of individuals to mount an appropriate immune response and may be inadequate in malnourished persons," scientists in Ouro Preto, Brazil report.

"In this study, we used a mouse model to verify the effect of combined protein, iron and zinc deficiency in the response to Leishmania chagasi antigen vaccine. BALB/c mice were fed with a low-protein (3% casein), iron- and zinc-deficient diet or control diet (14% casein and sufficient in zinc and iron). After malnutrition establishment, mice were...


Source: Vaccine Weekly (2009-02-18)

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