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Hepatitis B Virus
Research in the area of hepatitis B virus reported from P. Carotenuto and colleagues
February 18th, 2009
According to recent research published in the Journal of Medical Virology, "T lymphocyte responses to hepatitis B virus (HBV) core antigen (HBcAg) are vigorous and easily detectable in vitro during recovery from acute hepatitis B but significantly weaker in patients with chronic HBV infection. In contrast, T cell responses to hepatitis B surface antigen (HBsAg) are almost undetectable during infection and even in a substantial fraction of subjects receiving vaccination with HBsAg." "The aim of this study was to investigate whether the use of dendritic cells (DCs) in an in vitro assay could increase the detection of HBV-specific T cells in these conditions....
Source: Vaccine Weekly (2009-02-18)
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