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Vaccine Weekly

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Life Sciences



New findings from University of Michigan in the area of life sciences published



February 25th, 2009

"Manufacturers of vaccines and other biologicals are under increasing pressure from regulatory agencies to develop production methods that are completely animal-component-free. In order to comply with this demand, alternative cell culture substrates to those now on the market, primarily collagen or gelatin, must be found," researchers in the United States report.

"In this paper, we have tested a number of possible substitutes including recombinant collagen, a 100-kDa recombinant gelatin fragment and a peptide derived from a cell-binding region of type I collagen. The small 15-amino acid peptide did not support attachment of human fibroblasts in monolayer culture. The...


Source: Vaccine Weekly (2009-02-25)

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