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DNA Vaccines
New DNA vaccines research from Chonbuk National University, Bio-Safety Research Institute outlined
February 25th, 2009
Investigators publish new data in the report 'Genetic co-transfer of CCR7 ligands enhances immunity and prolongs survival against virulent challenge of pseudorabies virus.' "The CC chemokine receptor 7 (CCR7) and cognate CCR7 ligands, CCL19 and CCL21, help establish microenvironments in lymphoid tissue that can facilitate encounters between naive T cells and mature dendritic cells (DCs). This study was conducted to determine if CCR7 ligands can augment the immunogenicity of a DNA vaccine that expresses glycoprotein B (gB) of the pseudorabies virus (PrV)," scientists in Korea report. "The genetic co-transfer of CCR7 ligands along with a PrV DNA vaccine increased the...
Source: Vaccine Weekly (2009-02-25)
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